The intraoperative parathyroid testing service is provided by the lab to surgeons operating to remove parathyroid hormone producing tumors in the neck. Concentrations of the hormone in the blood markedly decrease within minutes after complete removal of such tumors, but remain elevated if the tumor remains, indicating the need for additional surgical exploration and excision. Intraoperative parathyroid hormone testing is the single best predictor of the success or failure of tumor removal. This stringent time limit can only be met with (1) excellent ongoing communication between the surgical team and the lab, (2) lab resources dedicated to the intra op testing, and (3) rapid testing methods that are complete within 10 minutes, preferably using reliable, automated analyzers that have been pre-calibrated and quality controlled. Since its inception at Mount Sinai Hospital in February 2009, intraoperative parathyroid hormone testing has been applied to over 200 operations to remove parathyroid hormone producing tumors. The Lab has consistently reported results within the 15 minute acceptable limit, while the results themselves have successfully predicted the clinical outcome in 100% of cases, well in excess of the 90% success rate achieved prior to the advent of intraoperative parathyroid hormone testing.
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